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Pedigree Analysis

How can Pedigree Analysis help my lame horse?
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Genetic Defects

Why is it important to know if your horse has genetic defects?
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Genetic Assets

Genetics can help with desirable traits too ...
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Color Genetics

Genetics are not only useful for detecting genetic diseases and genetic assets
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GT is Thrombosenia - a recessive disorder

Thrombasthenia is a bleeding disorder where the horses blood doesn't clot properly, these horses bleed excessively. 
Symptoms include weakness in the hind end, trouble getting up, cold limbs, low pulse

There is no effective treatment.

It is found in Throughbreds.

Genetic Codes for GT:

N/N Normal Cannot produce an affected foal

N/gt1 Horse is a carrier of GT, and can passto to approximately 50% of any offspring. If bred to another N/gt1 carrier, approximately 25% of the offspring will be normal, 50% will be carriers, and 25% will be affected.

N/gt2 Horse is a carrier of GT, and can pass the allele on to approximately 50% of any offspring. If bred to another N/gt2 carrier, approximately 25% of the offspring will be normal, 50% will be carriers, and 25% will be affected.

gt1/gt1 The horse is affected with GT. If bred to a normal animal, 100% of the offspring will be carriers. If bred to a N/gt1 carrier, 50% of the offspring will be carriers and 50% will be affected.

gt2/gt2 The horse is affected with GT. If bred to a normal animal, 100% of the offspring will be carriers. If bred to a N/gt2 carrier, 50% of the offspring will be carriers and 50% will be affected.

gt1/gt2 The horse is affected with GT. If bred to a normal animal, 100% of the offspring will be carriers. If bred to a N/gt1 or N/gt2 carrier, 50% of the offspring will be carriers and 50% will be affected.

Recommendations:
– Carriers may be bred to normal animals (N/gt1/gt2 x N/N) without any risk of producing affected offspring. The offspring should also be tested before breeding to determine if they are carriers or normal.
– Breeding two carriers (N/gt1/gt2 x N/gt1/gt2) is not recommended due to the possibility of 25% of the offspring being affected.

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